A cytotoxic waste box is a specialized, rigid container specifically designed for the safe disposal of materials contaminated with cytotoxic (antineoplastic) drugs, which are highly toxic and can cause cellular damage, mutations, or cancer. These drugs are commonly used in chemotherapy and research. The boxes are typically made from puncture-resistant cardboard or plastic, often featuring an inner liner and a secure, tamper-proof lid to prevent leaks and spills during handling and transport. They are easily identifiable by their distinctive color, often purple or yellow, and prominently display the international cytotoxic hazard symbol and clear warnings. The purpose of these boxes is to isolate and safely contain all items that have come into contact with cytotoxic agents, including used vials, syringes, IV bags, gowns, gloves, and absorbent pads. By providing a dedicated and robust disposal solution at the point of use, these boxes minimize the risk of exposure to healthcare workers, prevent environmental contamination, and ensure that this extremely hazardous waste is managed separately from other medical waste streams. The contents of cytotoxic waste boxes require specialized high-temperature incineration at licensed facilities to completely destroy the toxic compounds, highlighting their critical role in comprehensive and compliant medical waste management.